Isocitrate Dehydrogenase 2 Inhibitor [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Death | 650 | 1 | 650 | 14 | 0 |
| Fatigue | 229 | 2 | 6 | 43 | 0 |
| Off label use | 213 | 1 | 26 | 35 | 3 |
| Nausea | 213 | 2 | 6 | 42 | 0 |
| Acute myeloid leukaemia | 163 | 1 | 95 | 43 | 3 |
| Diarrhoea | 156 | 2 | 1 | 36 | 0 |
| Hospitalisation | 149 | 1 | 2 | 145 | 0 |
| Decreased appetite | 122 | 1 | 3 | 35 | 0 |
| Drug ineffective | 115 | 2 | 7 | 16 | 0 |
| Platelet count decreased | 113 | 1 | 3 | 45 | 0 |
| Differentiation syndrome | 102 | 1 | 19 | 66 | 11 |
| Pneumonia | 97 | 2 | 14 | 72 | 5 |
| Pyrexia | 90 | 1 | 9 | 71 | 3 |
| Asthenia | 89 | 1 | 2 | 39 | 1 |
| Full blood count decreased | 75 | 1 | 2 | 37 | 1 |
| Sepsis | 71 | 1 | 36 | 43 | 16 |
| Vomiting | 70 | 2 | 2 | 19 | 0 |
| Dyspnoea | 69 | 1 | 3 | 36 | 2 |
| White blood cell count decreased | 63 | 1 | 2 | 24 | 0 |
| Headache | 60 | 2 | 1 | 7 | 0 |
| Febrile neutropenia | 58 | 1 | 7 | 53 | 7 |
| Constipation | 57 | 1 | 0 | 12 | 0 |
| Dizziness | 56 | 2 | 0 | 13 | 1 |
| Blood bilirubin increased | 53 | 2 | 4 | 15 | 0 |
| Fall | 49 | 2 | 6 | 31 | 2 |
| Haemoglobin decreased | 48 | 1 | 2 | 20 | 0 |
| Rash | 47 | 1 | 0 | 10 | 0 |
| Infection | 42 | 1 | 6 | 31 | 1 |
| Adverse event | 42 | 1 | 1 | 14 | 2 |
| Weight decreased | 41 | 1 | 2 | 10 | 0 |