Janus Kinase Inhibitors [MoA]: Side Effects & Safety Data for 6 Drugs
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Janus Kinase Inhibitors [MoA] includes 6 drugs with a combined 303,277 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
6
Drugs in Class
303,277
Combined Reports
All Janus Kinase Inhibitors [MoA] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| TOFACITINIB | XELJANZ XR | 155,647 | 7,847 | 21,976 | 5.0% |
| RUXOLITINIB | OPZELURA | 68,133 | 10,908 | 14,461 | 16.0% |
| UPADACITINIB | Rinvoq | 65,656 | 2,406 | 15,931 | 3.7% |
| BARICITINIB | Olumiant | 8,108 | 717 | 2,498 | 8.8% |
| ABROCITINIB | CIBINQO | 3,170 | 57 | 329 | 1.8% |
| PACRITINIB | Vonjo | 2,563 | 292 | 455 | 11.4% |
Common Side Effects in Janus Kinase Inhibitors [MoA] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Drug ineffective | 36,584 | 1,699 |
| Pain | 28,165 | 1,902 |
| Off label use | 26,599 | 3,418 |
| Fatigue | 21,905 | 2,034 |
| Arthralgia | 20,893 | 1,624 |
| Condition aggravated | 18,930 | 1,661 |
| Rheumatoid arthritis | 15,330 | 1,775 |
| Headache | 15,269 | 1,497 |
| Diarrhoea | 12,502 | 1,618 |
| Pain in extremity | 12,371 | 1,100 |