Janus Kinase Inhibitors [MoA] — Common Side Effects

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Side Effect	Total Reports	Drugs	Deaths	Hosp.	Life-Threat.
Drug ineffective	36,584	6	1,699	5,356	1,908
Pain	28,165	6	1,902	6,025	2,158
Off label use	26,599	6	3,418	5,440	2,309
Fatigue	21,905	6	2,034	5,227	2,160
Arthralgia	20,893	6	1,624	4,663	1,837
Condition aggravated	18,930	6	1,661	4,224	1,813
Rheumatoid arthritis	15,330	4	1,775	3,982	2,109
Headache	15,269	6	1,497	3,280	1,610
Diarrhoea	12,502	6	1,618	3,720	1,669
Pain in extremity	12,371	6	1,100	2,879	1,033
Malaise	12,172	6	1,590	3,673	1,462
Joint swelling	12,149	6	1,802	3,273	2,117
Nausea	11,670	6	1,284	3,243	1,492
Death	11,629	6	11,520	1,177	91
Rash	11,361	6	1,784	3,448	2,085
Peripheral swelling	10,262	6	1,424	3,012	1,458
Nasopharyngitis	10,039	6	1,419	2,528	1,495
Pneumonia	9,490	6	2,008	5,698	1,287
Abdominal discomfort	9,403	6	1,517	2,748	1,829
Covid-19	9,332	6	519	2,644	108
Musculoskeletal stiffness	8,800	4	1,298	2,291	1,582
Dyspnoea	8,796	6	1,441	3,677	1,374
Alopecia	8,563	6	1,476	2,553	1,879
Swelling	8,561	6	1,667	2,789	1,987
Infection	8,445	6	1,489	3,313	1,316
Weight increased	8,267	6	1,596	2,547	1,686
Product dose omission issue	8,203	6	83	887	20
Drug intolerance	8,007	6	1,306	2,321	1,681
Arthropathy	7,990	4	1,462	3,075	1,904
Pyrexia	7,931	6	1,504	4,090	1,507