Phosphodiesterase 3 Inhibitor [EPC] — Common Side Effects
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| Side Effect | Total Reports | Drugs | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| Drug ineffective | 425 | 3 | 58 | 230 | 154 |
| Off label use | 140 | 2 | 17 | 78 | 35 |
| Death | 127 | 2 | 127 | 17 | 2 |
| Dyspnoea | 121 | 3 | 2 | 51 | 7 |
| Hypotension | 97 | 2 | 30 | 49 | 26 |
| Diarrhoea | 76 | 3 | 12 | 27 | 3 |
| Condition aggravated | 76 | 3 | 13 | 37 | 15 |
| Headache | 71 | 2 | 5 | 16 | 5 |
| Dizziness | 70 | 3 | 4 | 26 | 5 |
| Atrial fibrillation | 60 | 3 | 7 | 32 | 9 |
| Nausea | 58 | 3 | 12 | 32 | 4 |
| Tachycardia | 56 | 3 | 4 | 24 | 8 |
| Ventricular tachycardia | 54 | 2 | 5 | 32 | 23 |
| Drug ineffective for unapproved indication | 53 | 2 | 9 | 39 | 24 |
| Gastrointestinal haemorrhage | 52 | 1 | 1 | 44 | 2 |
| Cardiac failure | 51 | 2 | 11 | 37 | 12 |
| Asthenia | 51 | 3 | 7 | 26 | 3 |
| Acute kidney injury | 48 | 2 | 8 | 30 | 7 |
| Pneumonia | 44 | 2 | 16 | 27 | 5 |
| Cardiac arrest | 44 | 2 | 23 | 26 | 18 |
| Vomiting | 43 | 2 | 10 | 25 | 3 |
| Cardiogenic shock | 41 | 2 | 13 | 33 | 27 |
| Back pain | 40 | 2 | 0 | 6 | 0 |
| Product use in unapproved indication | 39 | 2 | 9 | 18 | 8 |
| Palpitations | 39 | 2 | 3 | 6 | 0 |
| Anaemia | 39 | 1 | 2 | 24 | 1 |
| Cerebral infarction | 35 | 1 | 6 | 23 | 5 |
| Chest pain | 33 | 2 | 5 | 17 | 5 |
| Melaena | 32 | 1 | 6 | 20 | 3 |
| Haemorrhage | 32 | 2 | 6 | 13 | 4 |