Poly(ADP-Ribose) Polymerase Inhibitor [EPC]: Side Effects & Safety Data for 4 Drugs
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Poly(ADP-Ribose) Polymerase Inhibitor [EPC] includes 4 drugs with a combined 49,625 adverse event reports in the FDA FAERS database. Compare their safety profiles, side effects, and outcomes below.
4
Drugs in Class
49,625
Combined Reports
All Poly(ADP-Ribose) Polymerase Inhibitor [EPC] Drugs Ranked by Reports
| Drug | Brand Name | Reports | Deaths | Hosp. | Death Rate |
|---|---|---|---|---|---|
| NIRAPARIB | ZEJULA | 21,634 | 1,370 | 4,892 | 6.3% |
| OLAPARIB | Lynparza | 18,274 | 5,496 | 3,471 | 30.1% |
| RUCAPARIB CAMSYLATE | Rubraca | 8,240 | 448 | 1,148 | 5.4% |
| TALAZOPARIB | Talzenna | 1,477 | 278 | 553 | 18.8% |
Common Side Effects in Poly(ADP-Ribose) Polymerase Inhibitor [EPC] Drugs
| Side Effect | Reports | Deaths |
|---|---|---|
| Nausea | 9,648 | 354 |
| Fatigue | 9,248 | 292 |
| Death | 5,768 | 5,767 |
| Constipation | 5,255 | 145 |
| Platelet count decreased | 5,050 | 191 |
| Malignant neoplasm progression | 4,395 | 507 |
| Anaemia | 3,610 | 294 |
| Vomiting | 3,457 | 208 |
| Off label use | 3,316 | 365 |
| Insomnia | 3,252 | 67 |