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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Poly(ADP-Ribose) Polymerase Inhibitor [EPC] — Common Side Effects

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Side Effect Total Reports Drugs Deaths Hosp. Life-Threat.
Nausea 9,648 4 354 2,019 260
Fatigue 9,248 4 292 1,774 232
Death 5,768 4 5,767 320 37
Constipation 5,255 4 145 1,184 150
Platelet count decreased 5,050 4 191 1,440 466
Malignant neoplasm progression 4,395 4 507 496 47
Anaemia 3,610 4 294 1,160 306
Vomiting 3,457 4 208 1,099 113
Off label use 3,316 4 365 628 40
Insomnia 3,252 3 67 618 101
Headache 3,166 4 61 653 90
Decreased appetite 3,125 4 170 837 103
Asthenia 3,052 4 151 927 123
Product dose omission issue 2,714 3 47 588 18
Carbohydrate antigen 125 increased 2,710 3 66 535 83
Blood pressure increased 2,629 3 53 589 89
Haemoglobin decreased 2,567 4 92 752 190
Diarrhoea 2,432 4 135 586 60
Dizziness 2,334 4 55 561 79
Dyspnoea 2,207 4 126 770 95
Drug ineffective 2,168 4 116 274 44
White blood cell count decreased 2,021 4 56 527 155
Malaise 1,860 4 98 532 68
Red blood cell count decreased 1,801 4 41 443 89
Arthralgia 1,734 4 27 336 35
Neuropathy peripheral 1,732 3 32 280 38
Pain 1,704 4 66 443 39
Thrombocytopenia 1,606 4 152 559 302
Hypertension 1,518 3 39 340 52
Weight decreased 1,436 4 64 421 52
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