Does ALEMTUZUMAB Cause Leukoencephalopathy? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Leukoencephalopathy have been filed in association with ALEMTUZUMAB (Campath). This represents 0.1% of all adverse event reports for ALEMTUZUMAB.
11
Reports of Leukoencephalopathy with ALEMTUZUMAB
0.1%
of all ALEMTUZUMAB reports
2
Deaths
6
Hospitalizations
How Dangerous Is Leukoencephalopathy From ALEMTUZUMAB?
Of the 11 reports, 2 (18.2%) resulted in death, 6 (54.5%) required hospitalization, and 3 (27.3%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for ALEMTUZUMAB.
What Other Side Effects Does ALEMTUZUMAB Cause?
Headache (1,808)
Fatigue (1,744)
Pyrexia (1,441)
Off label use (1,259)
Rash (1,094)
Nausea (1,053)
Dyspnoea (855)
Lymphocyte count decreased (852)
Asthenia (841)
Multiple sclerosis relapse (836)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which ALEMTUZUMAB Alternatives Have Lower Leukoencephalopathy Risk?
ALEMTUZUMAB vs ALENDRONATE
ALEMTUZUMAB vs ALENDRONATE\CHOLECALCIFEROL
ALEMTUZUMAB vs ALENDRONIC ACID
ALEMTUZUMAB vs ALEVE
ALEMTUZUMAB vs ALEVE CAPLET