Does RITUXIMAB Cause Leukoencephalopathy? 118 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 118 reports of Leukoencephalopathy have been filed in association with RITUXIMAB (Rituxan). This represents 0.1% of all adverse event reports for RITUXIMAB.
118
Reports of Leukoencephalopathy with RITUXIMAB
0.1%
of all RITUXIMAB reports
29
Deaths
45
Hospitalizations
How Dangerous Is Leukoencephalopathy From RITUXIMAB?
Of the 118 reports, 29 (24.6%) resulted in death, 45 (38.1%) required hospitalization, and 2 (1.7%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for RITUXIMAB.
What Other Side Effects Does RITUXIMAB Cause?
Off label use (39,751)
Drug ineffective (32,186)
Rheumatoid arthritis (19,850)
Pain (16,675)
Fatigue (15,602)
Arthralgia (12,529)
Rash (12,102)
Drug intolerance (11,876)
Infusion related reaction (11,871)
Joint swelling (11,170)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
METHADONE (76)
Which RITUXIMAB Alternatives Have Lower Leukoencephalopathy Risk?
RITUXIMAB vs RITUXIMAB-ABBS
RITUXIMAB vs RITUXIMAB-ARRX
RITUXIMAB vs RITUXIMAB-PVVR
RITUXIMAB vs RIVAROXABAN
RITUXIMAB vs RIVASTIGMINE