Does TACROLIMUS Cause Leukoencephalopathy? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Leukoencephalopathy have been filed in association with TACROLIMUS (Tacrolimus). This represents 0.1% of all adverse event reports for TACROLIMUS.
79
Reports of Leukoencephalopathy with TACROLIMUS
0.1%
of all TACROLIMUS reports
10
Deaths
44
Hospitalizations
How Dangerous Is Leukoencephalopathy From TACROLIMUS?
Of the 79 reports, 10 (12.7%) resulted in death, 44 (55.7%) required hospitalization, and 7 (8.9%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for TACROLIMUS.
What Other Side Effects Does TACROLIMUS Cause?
Off label use (8,718)
Drug ineffective (6,214)
Product use in unapproved indication (5,057)
Acute kidney injury (4,005)
Transplant rejection (3,526)
Cytomegalovirus infection (3,320)
Covid-19 (3,201)
Drug interaction (2,896)
Diarrhoea (2,854)
Toxicity to various agents (2,845)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
CAPECITABINE (77)
METHADONE (76)
Which TACROLIMUS Alternatives Have Lower Leukoencephalopathy Risk?
TACROLIMUS vs TACROLIMUS\TACROLIMUS ANHYDROUS
TACROLIMUS vs TADALAFIL
TACROLIMUS vs TAFAMIDIS
TACROLIMUS vs TAFAMIDIS MEGLUMINE
TACROLIMUS vs TAFASITAMAB