Does CYTARABINE Cause Leukoencephalopathy? 208 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 208 reports of Leukoencephalopathy have been filed in association with CYTARABINE (cytarabine). This represents 0.5% of all adverse event reports for CYTARABINE.
208
Reports of Leukoencephalopathy with CYTARABINE
0.5%
of all CYTARABINE reports
47
Deaths
88
Hospitalizations
How Dangerous Is Leukoencephalopathy From CYTARABINE?
Of the 208 reports, 47 (22.6%) resulted in death, 88 (42.3%) required hospitalization, and 16 (7.7%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 208 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
METHADONE (76)
Which CYTARABINE Alternatives Have Lower Leukoencephalopathy Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB