Does VINCRISTINE Cause Leukoencephalopathy? 138 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 138 reports of Leukoencephalopathy have been filed in association with VINCRISTINE (VinCRIStine Sulfate). This represents 0.2% of all adverse event reports for VINCRISTINE.
138
Reports of Leukoencephalopathy with VINCRISTINE
0.2%
of all VINCRISTINE reports
21
Deaths
79
Hospitalizations
How Dangerous Is Leukoencephalopathy From VINCRISTINE?
Of the 138 reports, 21 (15.2%) resulted in death, 79 (57.2%) required hospitalization, and 7 (5.1%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VINCRISTINE. However, 138 reports have been filed with the FAERS database.
What Other Side Effects Does VINCRISTINE Cause?
Febrile neutropenia (8,676)
Off label use (6,562)
Disease progression (5,252)
Neutropenia (4,982)
Drug ineffective (4,084)
Pyrexia (3,460)
Product use in unapproved indication (3,073)
Thrombocytopenia (2,940)
Sepsis (2,791)
Anaemia (2,603)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
METHADONE (76)
Which VINCRISTINE Alternatives Have Lower Leukoencephalopathy Risk?
VINCRISTINE vs VINDESINE
VINCRISTINE vs VINORELBINE
VINCRISTINE vs VINORELBINE\VINORELBINE
VINCRISTINE vs VIREAD
VINCRISTINE vs VISIPAQUE