Does ALPELISIB Cause Intestinal perforation? 10 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10 reports of Intestinal perforation have been filed in association with ALPELISIB (PIQRAY). This represents 0.1% of all adverse event reports for ALPELISIB.
10
Reports of Intestinal perforation with ALPELISIB
0.1%
of all ALPELISIB reports
6
Deaths
6
Hospitalizations
How Dangerous Is Intestinal perforation From ALPELISIB?
Of the 10 reports, 6 (60.0%) resulted in death, 6 (60.0%) required hospitalization, and 1 (10.0%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ALPELISIB. However, 10 reports have been filed with the FAERS database.
What Other Side Effects Does ALPELISIB Cause?
Hyperglycaemia (1,575)
Rash (1,393)
Diarrhoea (1,336)
Blood glucose increased (1,105)
Death (921)
Nausea (860)
Fatigue (817)
Decreased appetite (546)
Weight decreased (508)
Malignant neoplasm progression (497)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which ALPELISIB Alternatives Have Lower Intestinal perforation Risk?
ALPELISIB vs ALPHA.-LIPOIC ACID
ALPELISIB vs ALPHA.-TOCOPHEROL
ALPELISIB vs ALPHA.-TOCOPHEROL, D-
ALPELISIB vs ALPHA.-TOCOPHEROL, DL-
ALPELISIB vs ALPHA.1-PROTEINASE INHIBITOR HUMAN