Does APREMILAST Cause Intestinal perforation? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Intestinal perforation have been filed in association with APREMILAST (Otezla). This represents 0.0% of all adverse event reports for APREMILAST.
9
Reports of Intestinal perforation with APREMILAST
0.0%
of all APREMILAST reports
1
Deaths
9
Hospitalizations
How Dangerous Is Intestinal perforation From APREMILAST?
Of the 9 reports, 1 (11.1%) resulted in death, 9 (100.0%) required hospitalization, and 1 (11.1%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which APREMILAST Alternatives Have Lower Intestinal perforation Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA