Does AXITINIB Cause Hyperammonaemia? 9 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Hyperammonaemia have been filed in association with AXITINIB (INLYTA). This represents 0.1% of all adverse event reports for AXITINIB.
9
Reports of Hyperammonaemia with AXITINIB
0.1%
of all AXITINIB reports
1
Deaths
8
Hospitalizations
How Dangerous Is Hyperammonaemia From AXITINIB?
Of the 9 reports, 1 (11.1%) resulted in death, 8 (88.9%) required hospitalization, and 2 (22.2%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for AXITINIB. However, 9 reports have been filed with the FAERS database.
What Other Side Effects Does AXITINIB Cause?
Death (2,222)
Diarrhoea (2,187)
Fatigue (1,816)
Neoplasm progression (1,315)
Hypertension (1,146)
Off label use (1,075)
Nausea (955)
Decreased appetite (920)
Dysphonia (871)
Disease progression (768)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which AXITINIB Alternatives Have Lower Hyperammonaemia Risk?
AXITINIB vs AZACITIDINE
AXITINIB vs AZATHIOPRINE
AXITINIB vs AZD-1222
AXITINIB vs AZELAIC ACID
AXITINIB vs AZELASTINE