Does BEVACIZUMAB Cause Leukoencephalopathy? 63 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 63 reports of Leukoencephalopathy have been filed in association with BEVACIZUMAB (JOBEVNE). This represents 0.1% of all adverse event reports for BEVACIZUMAB.
63
Reports of Leukoencephalopathy with BEVACIZUMAB
0.1%
of all BEVACIZUMAB reports
8
Deaths
20
Hospitalizations
How Dangerous Is Leukoencephalopathy From BEVACIZUMAB?
Of the 63 reports, 8 (12.7%) resulted in death, 20 (31.7%) required hospitalization, and 3 (4.8%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BEVACIZUMAB. However, 63 reports have been filed with the FAERS database.
What Other Side Effects Does BEVACIZUMAB Cause?
Off label use (12,094)
Death (8,493)
Diarrhoea (4,911)
Disease progression (4,653)
Fatigue (4,572)
Nausea (4,357)
Hypertension (4,309)
Anaemia (3,221)
Vomiting (3,193)
Neutropenia (2,875)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which BEVACIZUMAB Alternatives Have Lower Leukoencephalopathy Risk?
BEVACIZUMAB vs BEVACIZUMAB-AWWB
BEVACIZUMAB vs BEVACIZUMAB-BVZR
BEVACIZUMAB vs BEVACIZUMAB-MALY
BEVACIZUMAB vs BEXAROTENE
BEVACIZUMAB vs BEYAZ