Does BINIMETINIB Cause Hepatotoxicity? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Hepatotoxicity have been filed in association with BINIMETINIB (MEKTOVI). This represents 0.3% of all adverse event reports for BINIMETINIB.
20
Reports of Hepatotoxicity with BINIMETINIB
0.3%
of all BINIMETINIB reports
0
Deaths
7
Hospitalizations
How Dangerous Is Hepatotoxicity From BINIMETINIB?
Of the 20 reports, 7 (35.0%) required hospitalization, and 1 (5.0%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for BINIMETINIB.
What Other Side Effects Does BINIMETINIB Cause?
Off label use (902)
Death (719)
Nausea (657)
Fatigue (562)
Diarrhoea (521)
Product use in unapproved indication (508)
Pyrexia (490)
Neoplasm progression (387)
Vomiting (375)
Rash (360)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which BINIMETINIB Alternatives Have Lower Hepatotoxicity Risk?
BINIMETINIB vs BIOFLAVONOIDS
BINIMETINIB vs BIOTIN
BINIMETINIB vs BIPERIDEN
BINIMETINIB vs BIRCH TRITERPENES
BINIMETINIB vs BISACODYL