Does CAPECITABINE Cause Hyperammonaemia? 51 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 51 reports of Hyperammonaemia have been filed in association with CAPECITABINE (Capecitabine). This represents 0.1% of all adverse event reports for CAPECITABINE.
51
Reports of Hyperammonaemia with CAPECITABINE
0.1%
of all CAPECITABINE reports
1
Deaths
35
Hospitalizations
How Dangerous Is Hyperammonaemia From CAPECITABINE?
Of the 51 reports, 1 (2.0%) resulted in death, 35 (68.6%) required hospitalization, and 3 (5.9%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CAPECITABINE. However, 51 reports have been filed with the FAERS database.
What Other Side Effects Does CAPECITABINE Cause?
Diarrhoea (9,277)
Nausea (6,248)
Palmar-plantar erythrodysaesthesia syndrome (5,294)
Fatigue (5,018)
Death (4,422)
Vomiting (4,111)
Disease progression (3,808)
Off label use (3,193)
Malignant neoplasm progression (2,425)
Asthenia (2,352)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which CAPECITABINE Alternatives Have Lower Hyperammonaemia Risk?
CAPECITABINE vs CAPIVASERTIB
CAPECITABINE vs CAPLACIZUMAB
CAPECITABINE vs CAPLACIZUMAB-YHDP
CAPECITABINE vs CAPMATINIB
CAPECITABINE vs CAPREOMYCIN