Does CETUXIMAB Cause Intestinal perforation? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Intestinal perforation have been filed in association with CETUXIMAB (ERBITUX). This represents 0.2% of all adverse event reports for CETUXIMAB.
27
Reports of Intestinal perforation with CETUXIMAB
0.2%
of all CETUXIMAB reports
7
Deaths
14
Hospitalizations
How Dangerous Is Intestinal perforation From CETUXIMAB?
Of the 27 reports, 7 (25.9%) resulted in death, 14 (51.9%) required hospitalization, and 5 (18.5%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CETUXIMAB. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does CETUXIMAB Cause?
Off label use (1,549)
Rash (883)
Diarrhoea (874)
Neutropenia (744)
Nausea (663)
Malignant neoplasm progression (662)
Dyspnoea (542)
Decreased appetite (541)
Vomiting (533)
Death (518)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which CETUXIMAB Alternatives Have Lower Intestinal perforation Risk?
CETUXIMAB vs CETYLPYRIDINIUM
CETUXIMAB vs CEVIMELINE
CETUXIMAB vs CHAMPIX
CETUXIMAB vs CHANTIX
CETUXIMAB vs CHENODIOL