Does CISPLATIN Cause Leukoencephalopathy? 48 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 48 reports of Leukoencephalopathy have been filed in association with CISPLATIN (CISplatin). This represents 0.1% of all adverse event reports for CISPLATIN.
48
Reports of Leukoencephalopathy with CISPLATIN
0.1%
of all CISPLATIN reports
6
Deaths
18
Hospitalizations
How Dangerous Is Leukoencephalopathy From CISPLATIN?
Of the 48 reports, 6 (12.5%) resulted in death, 18 (37.5%) required hospitalization, and 2 (4.2%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
Yes, Leukoencephalopathy is listed as a known adverse reaction in the official FDA drug label for CISPLATIN.
What Other Side Effects Does CISPLATIN Cause?
Off label use (4,359)
Disease progression (3,746)
Neutropenia (3,095)
Febrile neutropenia (3,010)
Nausea (2,923)
Drug ineffective (2,608)
Thrombocytopenia (2,565)
Anaemia (2,530)
Vomiting (2,326)
Diarrhoea (2,022)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which CISPLATIN Alternatives Have Lower Leukoencephalopathy Risk?
CISPLATIN vs CISPLATIN\CYTARABINE\DEXAMETHASONE
CISPLATIN vs CITALOPRAM
CISPLATIN vs CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITALOPRAM\CITALOPRAM HYDROBROMIDE
CISPLATIN vs CITICOLINE