Does CLOFARABINE Cause Hyperammonaemia? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Hyperammonaemia have been filed in association with CLOFARABINE (Clofarabine). This represents 0.4% of all adverse event reports for CLOFARABINE.
6
Reports of Hyperammonaemia with CLOFARABINE
0.4%
of all CLOFARABINE reports
6
Deaths
4
Hospitalizations
How Dangerous Is Hyperammonaemia From CLOFARABINE?
Of the 6 reports, 6 (100.0%) resulted in death, 4 (66.7%) required hospitalization.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOFARABINE. However, 6 reports have been filed with the FAERS database.
What Other Side Effects Does CLOFARABINE Cause?
Febrile neutropenia (201)
Off label use (158)
Drug ineffective (139)
Pyrexia (139)
Mucosal inflammation (89)
Sepsis (85)
Alanine aminotransferase increased (82)
Acute kidney injury (80)
Multiple organ dysfunction syndrome (77)
Aspartate aminotransferase increased (76)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which CLOFARABINE Alternatives Have Lower Hyperammonaemia Risk?
CLOFARABINE vs CLOFAZIMINE
CLOFARABINE vs CLOMETHIAZOLE
CLOFARABINE vs CLOMIPHENE
CLOFARABINE vs CLOMIPRAMINE
CLOFARABINE vs CLONAZEPAM