Does CLONAZEPAM Cause Hyperammonaemia? 70 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 70 reports of Hyperammonaemia have been filed in association with CLONAZEPAM (Clonazepam). This represents 0.2% of all adverse event reports for CLONAZEPAM.
70
Reports of Hyperammonaemia with CLONAZEPAM
0.2%
of all CLONAZEPAM reports
2
Deaths
32
Hospitalizations
How Dangerous Is Hyperammonaemia From CLONAZEPAM?
Of the 70 reports, 2 (2.9%) resulted in death, 32 (45.7%) required hospitalization, and 9 (12.9%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLONAZEPAM. However, 70 reports have been filed with the FAERS database.
What Other Side Effects Does CLONAZEPAM Cause?
Drug ineffective (5,088)
Toxicity to various agents (4,028)
Completed suicide (3,320)
Drug abuse (3,287)
Off label use (2,590)
Anxiety (2,376)
Somnolence (2,260)
Dyspnoea (1,987)
Depression (1,838)
Insomnia (1,836)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which CLONAZEPAM Alternatives Have Lower Hyperammonaemia Risk?
CLONAZEPAM vs CLONIDINE
CLONAZEPAM vs CLOPIDOGREL
CLONAZEPAM vs CLOPIDOGREL BESILATE
CLONAZEPAM vs CLOPIDOGREL BISULFATE
CLONAZEPAM vs CLORAZEPATE