Does CYCLOSPORINE Cause Hyperammonaemia? 36 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 36 reports of Hyperammonaemia have been filed in association with CYCLOSPORINE (Verkazia). This represents 0.1% of all adverse event reports for CYCLOSPORINE.
36
Reports of Hyperammonaemia with CYCLOSPORINE
0.1%
of all CYCLOSPORINE reports
19
Deaths
25
Hospitalizations
How Dangerous Is Hyperammonaemia From CYCLOSPORINE?
Of the 36 reports, 19 (52.8%) resulted in death, 25 (69.4%) required hospitalization, and 10 (27.8%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYCLOSPORINE. However, 36 reports have been filed with the FAERS database.
What Other Side Effects Does CYCLOSPORINE Cause?
Drug ineffective (11,172)
Off label use (6,860)
Eye irritation (5,806)
Product use in unapproved indication (5,019)
Condition aggravated (2,310)
Eye pain (2,197)
Drug intolerance (2,176)
Pneumonia (2,022)
Pyrexia (2,020)
Treatment failure (1,961)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which CYCLOSPORINE Alternatives Have Lower Hyperammonaemia Risk?
CYCLOSPORINE vs CYCLOSPORINE A
CYCLOSPORINE vs CYMBALTA
CYCLOSPORINE vs CYNODON DACTYLON POLLEN
CYCLOSPORINE vs CYPROHEPTADINE
CYCLOSPORINE vs CYPROTERONE