Does CYTARABINE Cause Neurotoxicity? 417 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 417 reports of Neurotoxicity have been filed in association with CYTARABINE (cytarabine). This represents 0.9% of all adverse event reports for CYTARABINE.
417
Reports of Neurotoxicity with CYTARABINE
0.9%
of all CYTARABINE reports
68
Deaths
110
Hospitalizations
How Dangerous Is Neurotoxicity From CYTARABINE?
Of the 417 reports, 68 (16.3%) resulted in death, 110 (26.4%) required hospitalization, and 49 (11.8%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CYTARABINE. However, 417 reports have been filed with the FAERS database.
What Other Side Effects Does CYTARABINE Cause?
Febrile neutropenia (6,142)
Off label use (4,183)
Pyrexia (2,992)
Neutropenia (2,558)
Disease progression (2,352)
Drug ineffective (2,281)
Thrombocytopenia (2,148)
Sepsis (2,013)
Myelosuppression (1,869)
Product use in unapproved indication (1,619)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which CYTARABINE Alternatives Have Lower Neurotoxicity Risk?
CYTARABINE vs CYTARABINE\DAUNORUBICIN
CYTARABINE vs DABIGATRAN
CYTARABINE vs DABIGATRAN ETEXILATE
CYTARABINE vs DABRAFENIB
CYTARABINE vs DABRAFENIB\TRAMETINIB