Does DABRAFENIB Cause Intestinal perforation? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Intestinal perforation have been filed in association with DABRAFENIB (Tafinlar). This represents 0.2% of all adverse event reports for DABRAFENIB.
42
Reports of Intestinal perforation with DABRAFENIB
0.2%
of all DABRAFENIB reports
11
Deaths
14
Hospitalizations
How Dangerous Is Intestinal perforation From DABRAFENIB?
Of the 42 reports, 11 (26.2%) resulted in death, 14 (33.3%) required hospitalization, and 6 (14.3%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for DABRAFENIB.
What Other Side Effects Does DABRAFENIB Cause?
Pyrexia (3,788)
Death (2,740)
Malignant neoplasm progression (1,667)
Fatigue (1,328)
Nausea (1,300)
Chills (1,235)
Rash (1,078)
Vomiting (907)
Diarrhoea (901)
Headache (697)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which DABRAFENIB Alternatives Have Lower Intestinal perforation Risk?
DABRAFENIB vs DABRAFENIB\TRAMETINIB
DABRAFENIB vs DACARBAZINE
DABRAFENIB vs DACLATASVIR
DABRAFENIB vs DACLIZUMAB
DABRAFENIB vs DACOMITINIB