Does DEXAMETHASONE Cause Hyperammonaemia? 72 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 72 reports of Hyperammonaemia have been filed in association with DEXAMETHASONE (Dexamethasone Sodium Phosphate). This represents 0.1% of all adverse event reports for DEXAMETHASONE.
72
Reports of Hyperammonaemia with DEXAMETHASONE
0.1%
of all DEXAMETHASONE reports
35
Deaths
50
Hospitalizations
How Dangerous Is Hyperammonaemia From DEXAMETHASONE?
Of the 72 reports, 35 (48.6%) resulted in death, 50 (69.4%) required hospitalization, and 30 (41.7%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEXAMETHASONE. However, 72 reports have been filed with the FAERS database.
What Other Side Effects Does DEXAMETHASONE Cause?
Off label use (13,439)
Plasma cell myeloma (9,207)
Drug ineffective (8,359)
Pneumonia (6,073)
Neutropenia (6,050)
Thrombocytopenia (5,873)
Diarrhoea (4,816)
Pyrexia (4,639)
Disease progression (4,545)
Febrile neutropenia (4,382)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which DEXAMETHASONE Alternatives Have Lower Hyperammonaemia Risk?
DEXAMETHASONE vs DEXAMETHASONE\DEXAMETHASONE
DEXAMETHASONE vs DEXAMETHASONE\NEOMYCIN
DEXAMETHASONE vs DEXAMETHASONE\NEOMYCIN\POLYMYXIN B
DEXAMETHASONE vs DEXAMETHASONE\TOBRAMYCIN
DEXAMETHASONE vs DEXCHLORPHENIRAMINE