Does DIVALPROEX Cause Neurotoxicity? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Neurotoxicity have been filed in association with DIVALPROEX (Divalproex Sodium). This represents 0.1% of all adverse event reports for DIVALPROEX.
12
Reports of Neurotoxicity with DIVALPROEX
0.1%
of all DIVALPROEX reports
3
Deaths
11
Hospitalizations
How Dangerous Is Neurotoxicity From DIVALPROEX?
Of the 12 reports, 3 (25.0%) resulted in death, 11 (91.7%) required hospitalization, and 1 (8.3%) were considered life-threatening.
Is Neurotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DIVALPROEX. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does DIVALPROEX Cause?
Drug ineffective (1,121)
Seizure (1,095)
Off label use (576)
Somnolence (545)
Drug interaction (540)
Nausea (526)
Weight increased (509)
Tremor (461)
Toxicity to various agents (452)
Vomiting (436)
What Other Drugs Cause Neurotoxicity?
AXICABTAGENE CILOLEUCEL (1,327)
OXALIPLATIN (1,272)
METHOTREXATE (1,083)
CYCLOPHOSPHAMIDE (763)
FLUOROURACIL (735)
PACLITAXEL (734)
TACROLIMUS (623)
BEVACIZUMAB (588)
VINCRISTINE (555)
CAPECITABINE (553)
Which DIVALPROEX Alternatives Have Lower Neurotoxicity Risk?
DIVALPROEX vs DOBUTAMINE
DIVALPROEX vs DOBUTAMINE\DOBUTAMINE
DIVALPROEX vs DOCETAXEL
DIVALPROEX vs DOCETAXEL ANHYDROUS
DIVALPROEX vs DOCETAXEL\DOCETAXEL ANHYDROUS