Does DURVALUMAB Cause Intestinal perforation? 38 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 38 reports of Intestinal perforation have been filed in association with DURVALUMAB (IMFINZI). This represents 0.2% of all adverse event reports for DURVALUMAB.
38
Reports of Intestinal perforation with DURVALUMAB
0.2%
of all DURVALUMAB reports
23
Deaths
24
Hospitalizations
How Dangerous Is Intestinal perforation From DURVALUMAB?
Of the 38 reports, 23 (60.5%) resulted in death, 24 (63.2%) required hospitalization, and 15 (39.5%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for DURVALUMAB.
What Other Side Effects Does DURVALUMAB Cause?
Death (2,817)
Malignant neoplasm progression (1,330)
Pneumonitis (827)
Radiation pneumonitis (786)
Pyrexia (573)
Diarrhoea (530)
Pneumonia (453)
Dyspnoea (444)
Interstitial lung disease (430)
Off label use (395)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which DURVALUMAB Alternatives Have Lower Intestinal perforation Risk?
DURVALUMAB vs DUTASTERIDE
DURVALUMAB vs DUTASTERIDE\TAMSULOSIN
DURVALUMAB vs DUVELISIB
DURVALUMAB vs DYDROGESTERONE
DURVALUMAB vs EBASTINE