Does ETOPOSIDE Cause Leukoencephalopathy? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Leukoencephalopathy have been filed in association with ETOPOSIDE (Avopef). This represents 0.1% of all adverse event reports for ETOPOSIDE.
31
Reports of Leukoencephalopathy with ETOPOSIDE
0.1%
of all ETOPOSIDE reports
8
Deaths
5
Hospitalizations
How Dangerous Is Leukoencephalopathy From ETOPOSIDE?
Of the 31 reports, 8 (25.8%) resulted in death, 5 (16.1%) required hospitalization, and 2 (6.5%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ETOPOSIDE. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does ETOPOSIDE Cause?
Off label use (6,495)
Febrile neutropenia (5,966)
Disease progression (3,776)
Drug ineffective (3,687)
Neutropenia (3,641)
Thrombocytopenia (3,085)
Product use in unapproved indication (2,774)
Anaemia (2,586)
Pyrexia (2,453)
Sepsis (2,211)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which ETOPOSIDE Alternatives Have Lower Leukoencephalopathy Risk?
ETOPOSIDE vs ETORICOXIB
ETOPOSIDE vs ETRASIMOD ARGININE
ETOPOSIDE vs ETRAVIRINE
ETOPOSIDE vs EUCALYPTOL\MENTHOL\METHYL SALICYLATE\THYMOL
ETOPOSIDE vs EVEROLIMUS