Does FILGRASTIM Cause Intestinal perforation? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Intestinal perforation have been filed in association with FILGRASTIM (NYPOZI txid). This represents 0.2% of all adverse event reports for FILGRASTIM.
23
Reports of Intestinal perforation with FILGRASTIM
0.2%
of all FILGRASTIM reports
10
Deaths
7
Hospitalizations
How Dangerous Is Intestinal perforation From FILGRASTIM?
Of the 23 reports, 10 (43.5%) resulted in death, 7 (30.4%) required hospitalization, and 2 (8.7%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FILGRASTIM. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does FILGRASTIM Cause?
Off label use (1,930)
Febrile neutropenia (1,570)
Neutropenia (1,431)
Death (1,213)
Pyrexia (1,085)
Diarrhoea (739)
Nausea (718)
Bone pain (706)
Thrombocytopenia (697)
Anaemia (626)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which FILGRASTIM Alternatives Have Lower Intestinal perforation Risk?
FILGRASTIM vs FILGRASTIM-AAFI
FILGRASTIM vs FILGRASTIM-SNDZ
FILGRASTIM vs FINASTERIDE
FILGRASTIM vs FINASTERIDE\TAMSULOSIN
FILGRASTIM vs FINERENONE