Does HYDROCORTISONE Cause Leukoencephalopathy? 46 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 46 reports of Leukoencephalopathy have been filed in association with HYDROCORTISONE (Hydrocortisone Cream Intensive Healing). This represents 0.2% of all adverse event reports for HYDROCORTISONE.
46
Reports of Leukoencephalopathy with HYDROCORTISONE
0.2%
of all HYDROCORTISONE reports
4
Deaths
17
Hospitalizations
How Dangerous Is Leukoencephalopathy From HYDROCORTISONE?
Of the 46 reports, 4 (8.7%) resulted in death, 17 (37.0%) required hospitalization, and 10 (21.7%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for HYDROCORTISONE. However, 46 reports have been filed with the FAERS database.
What Other Side Effects Does HYDROCORTISONE Cause?
Drug ineffective (6,176)
Off label use (4,382)
Pain (3,662)
Fatigue (3,642)
Rash (3,562)
Condition aggravated (3,333)
Systemic lupus erythematosus (3,175)
Abdominal discomfort (3,166)
Alopecia (3,125)
Swelling (3,056)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which HYDROCORTISONE Alternatives Have Lower Leukoencephalopathy Risk?
HYDROCORTISONE vs HYDROCORTISONE PROBUTATE
HYDROCORTISONE vs HYDROCORTISONE\HYDROCORTISONE
HYDROCORTISONE vs HYDROCORTISONE\NEOMYCIN\POLYMYXIN B
HYDROCORTISONE vs HYDROCORTISONE\PRAMOXINE
HYDROCORTISONE vs HYDROGEN PEROXIDE