Does LAMIVUDINE Cause Hyperammonaemia? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Hyperammonaemia have been filed in association with LAMIVUDINE (Lamivudine and Zidovudine). This represents 0.0% of all adverse event reports for LAMIVUDINE.
5
Reports of Hyperammonaemia with LAMIVUDINE
0.0%
of all LAMIVUDINE reports
4
Deaths
1
Hospitalizations
How Dangerous Is Hyperammonaemia From LAMIVUDINE?
Of the 5 reports, 4 (80.0%) resulted in death, 1 (20.0%) required hospitalization, and 3 (60.0%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LAMIVUDINE. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does LAMIVUDINE Cause?
Foetal exposure during pregnancy (1,905)
Virologic failure (1,894)
Drug resistance (1,889)
Pathogen resistance (1,733)
Viral mutation identified (1,631)
Treatment failure (933)
Exposure during pregnancy (846)
Drug interaction (744)
Drug ineffective (726)
Immune reconstitution inflammatory syndrome (625)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which LAMIVUDINE Alternatives Have Lower Hyperammonaemia Risk?
LAMIVUDINE vs LAMIVUDINE\NEVIRAPINE\ZIDOVUDINE
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR
LAMIVUDINE vs LAMIVUDINE\TENOFOVIR DISOPROXIL
LAMIVUDINE vs LAMIVUDINE\ZIDOVUDINE
LAMIVUDINE vs LAMOTRIGINE