Does LENVATINIB Cause Hyperammonaemia? 50 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 50 reports of Hyperammonaemia have been filed in association with LENVATINIB (Lenvima). This represents 0.2% of all adverse event reports for LENVATINIB.
50
Reports of Hyperammonaemia with LENVATINIB
0.2%
of all LENVATINIB reports
7
Deaths
39
Hospitalizations
How Dangerous Is Hyperammonaemia From LENVATINIB?
Of the 50 reports, 7 (14.0%) resulted in death, 39 (78.0%) required hospitalization, and 1 (2.0%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LENVATINIB. However, 50 reports have been filed with the FAERS database.
What Other Side Effects Does LENVATINIB Cause?
Diarrhoea (4,262)
Hypertension (4,152)
Fatigue (3,603)
Decreased appetite (3,257)
Malignant neoplasm progression (2,929)
Nausea (2,492)
Blood pressure increased (2,228)
Vomiting (1,962)
Asthenia (1,643)
Malaise (1,602)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which LENVATINIB Alternatives Have Lower Hyperammonaemia Risk?
LENVATINIB vs LEPONEX
LENVATINIB vs LERCANIDIPINE
LENVATINIB vs LETAIRIS
LENVATINIB vs LETERMOVIR
LENVATINIB vs LETROZOLE