Does LETROZOLE Cause Intestinal perforation? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Intestinal perforation have been filed in association with LETROZOLE (Letrozole). This represents 0.0% of all adverse event reports for LETROZOLE.
12
Reports of Intestinal perforation with LETROZOLE
0.0%
of all LETROZOLE reports
4
Deaths
3
Hospitalizations
How Dangerous Is Intestinal perforation From LETROZOLE?
Of the 12 reports, 4 (33.3%) resulted in death, 3 (25.0%) required hospitalization, and 7 (58.3%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which LETROZOLE Alternatives Have Lower Intestinal perforation Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL