Does LEUCOVORIN Cause Leukoencephalopathy? 38 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 38 reports of Leukoencephalopathy have been filed in association with LEUCOVORIN (LEUCOVORIN CALCIUM). This represents 0.2% of all adverse event reports for LEUCOVORIN.
38
Reports of Leukoencephalopathy with LEUCOVORIN
0.2%
of all LEUCOVORIN reports
7
Deaths
6
Hospitalizations
How Dangerous Is Leukoencephalopathy From LEUCOVORIN?
Of the 38 reports, 7 (18.4%) resulted in death, 6 (15.8%) required hospitalization, and 1 (2.6%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEUCOVORIN. However, 38 reports have been filed with the FAERS database.
What Other Side Effects Does LEUCOVORIN Cause?
Diarrhoea (2,594)
Neutropenia (2,291)
Nausea (1,977)
Neuropathy peripheral (1,557)
Disease progression (1,456)
Fatigue (1,443)
Vomiting (1,441)
Off label use (1,390)
Thrombocytopenia (1,181)
Pyrexia (1,148)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which LEUCOVORIN Alternatives Have Lower Leukoencephalopathy Risk?
LEUCOVORIN vs LEUCOVORIN\LEUCOVORIN
LEUCOVORIN vs LEUPROLIDE
LEUCOVORIN vs LEVALBUTEROL
LEUCOVORIN vs LEVAMISOLE
LEUCOVORIN vs LEVAQUIN