Does LORAZEPAM Cause Intestinal perforation? 35 Reports in FDA Database

Q: Does LORAZEPAM cause Intestinal perforation?

35 reports of Intestinal perforation have been filed with the FDA for LORAZEPAM, representing 0.1% of all LORAZEPAM adverse event reports.

Q: How dangerous is Intestinal perforation from LORAZEPAM?

Of 35 reports, 18 (51.4%) resulted in death and 33 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Intestinal perforation have been filed in association with LORAZEPAM (Lorazepam). This represents 0.1% of all adverse event reports for LORAZEPAM.

Reports of Intestinal perforation with LORAZEPAM

0.1%

of all LORAZEPAM reports

Deaths

Hospitalizations

How Dangerous Is Intestinal perforation From LORAZEPAM?

Of the 35 reports, 18 (51.4%) resulted in death, 33 (94.3%) required hospitalization, and 12 (34.3%) were considered life-threatening.

Is Intestinal perforation Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for LORAZEPAM. However, 35 reports have been filed with the FAERS database.

What Other Side Effects Does LORAZEPAM Cause?

Drug ineffective (3,775) Drug abuse (3,741) Toxicity to various agents (2,836) Completed suicide (2,340) Off label use (2,178) Somnolence (2,114) Sopor (2,042)