Does MACITENTAN Cause Hyperammonaemia? 8 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 8 reports of Hyperammonaemia have been filed in association with MACITENTAN (OPSYNVI). This represents 0.0% of all adverse event reports for MACITENTAN.
8
Reports of Hyperammonaemia with MACITENTAN
0.0%
of all MACITENTAN reports
2
Deaths
8
Hospitalizations
How Dangerous Is Hyperammonaemia From MACITENTAN?
Of the 8 reports, 2 (25.0%) resulted in death, 8 (100.0%) required hospitalization, and 1 (12.5%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MACITENTAN. However, 8 reports have been filed with the FAERS database.
What Other Side Effects Does MACITENTAN Cause?
Dyspnoea (8,315)
Death (5,864)
Headache (4,856)
Diarrhoea (3,669)
Pneumonia (3,531)
Nausea (3,463)
Hospitalisation (3,414)
Fatigue (3,172)
Fluid retention (2,861)
Dizziness (2,704)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which MACITENTAN Alternatives Have Lower Hyperammonaemia Risk?
MACITENTAN vs MACITENTAN\TADALAFIL
MACITENTAN vs MAGNESIUM
MACITENTAN vs MAGNESIUM ASPARTATE
MACITENTAN vs MAGNESIUM ASPARTATE\POTASSIUM ASPARTATE
MACITENTAN vs MAGNESIUM HYDROXIDE