Does MESNA Cause Acute hepatic failure? 9 Reports in FDA Database

Q: Does MESNA cause Acute hepatic failure?

9 reports of Acute hepatic failure have been filed with the FDA for MESNA, representing 0.2% of all MESNA adverse event reports.

Q: How dangerous is Acute hepatic failure from MESNA?

Of 9 reports, 3 (33.3%) resulted in death and 7 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 9 reports of Acute hepatic failure have been filed in association with MESNA (mesna). This represents 0.2% of all adverse event reports for MESNA.

Reports of Acute hepatic failure with MESNA

0.2%

of all MESNA reports

Deaths

Hospitalizations

How Dangerous Is Acute hepatic failure From MESNA?

Of the 9 reports, 3 (33.3%) resulted in death, 7 (77.8%) required hospitalization, and 6 (66.7%) were considered life-threatening.

Is Acute hepatic failure Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for MESNA. However, 9 reports have been filed with the FAERS database.

What Other Side Effects Does MESNA Cause?

Febrile neutropenia (707) Pyrexia (352) Off label use (299) Cystitis haemorrhagic (294) Disease progression (273) Neutropenia (238) Encephalopathy (226) Vomiting (200) Death (184) Pancytopenia (179)

What Other Drugs Cause Acute hepatic failure?

ACETAMINOPHEN (3,141) PREDNISONE (439) IBUPROFEN (412) RITUXIMAB (412) CYCLOPHOSPHAMIDE (411) DOXORUBICIN (385) VINCRISTINE (346) PREDNISOLONE (301) METHOTREXATE (285) DEXAMETHASONE (249)

Which MESNA Alternatives Have Lower Acute hepatic failure Risk?

MESNA vs METAMIZOLE MESNA vs METARAMINOL MESNA vs METAXALONE MESNA vs METFORMIN MESNA vs METFORMIN\PIOGLITAZONE

MESNA Full Profile All Acute hepatic failure Reports All Drugs Causing Acute hepatic failure MESNA Demographics