Does METFORMIN Cause Hyperammonaemia? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Hyperammonaemia have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.0% of all adverse event reports for METFORMIN.
23
Reports of Hyperammonaemia with METFORMIN
0.0%
of all METFORMIN reports
1
Deaths
22
Hospitalizations
How Dangerous Is Hyperammonaemia From METFORMIN?
Of the 23 reports, 1 (4.3%) resulted in death, 22 (95.7%) required hospitalization, and 1 (4.3%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which METFORMIN Alternatives Have Lower Hyperammonaemia Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN