Does METFORMIN Cause Intestinal perforation? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Intestinal perforation have been filed in association with METFORMIN (Metformin Hydrochloride). This represents 0.0% of all adverse event reports for METFORMIN.
27
Reports of Intestinal perforation with METFORMIN
0.0%
of all METFORMIN reports
3
Deaths
24
Hospitalizations
How Dangerous Is Intestinal perforation From METFORMIN?
Of the 27 reports, 3 (11.1%) resulted in death, 24 (88.9%) required hospitalization.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METFORMIN. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does METFORMIN Cause?
Lactic acidosis (16,316)
Acute kidney injury (11,361)
Diarrhoea (7,679)
Toxicity to various agents (5,669)
Metabolic acidosis (5,236)
Hypoglycaemia (5,047)
Drug ineffective (4,991)
Nausea (4,915)
Vomiting (4,624)
Blood glucose increased (4,038)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which METFORMIN Alternatives Have Lower Intestinal perforation Risk?
METFORMIN vs METFORMIN\PIOGLITAZONE
METFORMIN vs METFORMIN\ROSIGLITAZONE
METFORMIN vs METFORMIN\SAXAGLIPTIN
METFORMIN vs METFORMIN\SITAGLIPTIN
METFORMIN vs METFORMIN\VILDAGLIPTIN