Does METHADONE Cause Intestinal perforation? 34 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 34 reports of Intestinal perforation have been filed in association with METHADONE (METHADONE HYDROCHLORIDE). This represents 0.1% of all adverse event reports for METHADONE.
34
Reports of Intestinal perforation with METHADONE
0.1%
of all METHADONE reports
13
Deaths
31
Hospitalizations
How Dangerous Is Intestinal perforation From METHADONE?
Of the 34 reports, 13 (38.2%) resulted in death, 31 (91.2%) required hospitalization, and 13 (38.2%) were considered life-threatening.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHADONE. However, 34 reports have been filed with the FAERS database.
What Other Side Effects Does METHADONE Cause?
Drug dependence (5,739)
Toxicity to various agents (4,586)
Drug abuse (4,480)
Overdose (3,472)
Pain (2,754)
Death (2,716)
Emotional distress (2,388)
Drug withdrawal syndrome (2,127)
Foetal exposure during pregnancy (1,759)
Drug withdrawal syndrome neonatal (1,458)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which METHADONE Alternatives Have Lower Intestinal perforation Risk?
METHADONE vs METHAMPHETAMINE
METHADONE vs METHENAMINE HIPPURATE
METHADONE vs METHIMAZOLE
METHADONE vs METHOCARBAMOL
METHADONE vs METHOHEXITAL