Does METHIMAZOLE Cause Hepatotoxicity? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Hepatotoxicity have been filed in association with METHIMAZOLE (Methimazole). This represents 0.9% of all adverse event reports for METHIMAZOLE.
22
Reports of Hepatotoxicity with METHIMAZOLE
0.9%
of all METHIMAZOLE reports
1
Deaths
14
Hospitalizations
How Dangerous Is Hepatotoxicity From METHIMAZOLE?
Of the 22 reports, 1 (4.5%) resulted in death, 14 (63.6%) required hospitalization, and 4 (18.2%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHIMAZOLE. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does METHIMAZOLE Cause?
Drug ineffective (305)
Agranulocytosis (263)
Hyperthyroidism (206)
Off label use (143)
Hypothyroidism (98)
Foetal exposure during pregnancy (85)
Neutropenia (78)
Condition aggravated (76)
Thyrotoxic crisis (75)
Drug-induced liver injury (73)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which METHIMAZOLE Alternatives Have Lower Hepatotoxicity Risk?
METHIMAZOLE vs METHOCARBAMOL
METHIMAZOLE vs METHOHEXITAL
METHIMAZOLE vs METHOTREXATE
METHIMAZOLE vs METHOXSALEN
METHIMAZOLE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA