METHOTREXATE for Prophylaxis against graft versus host disease: Side Effects & Safety Data
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There are 5,226 adverse event reports in the FDA FAERS database where METHOTREXATE was used for Prophylaxis against graft versus host disease.
Most Reported Side Effects for METHOTREXATE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Drug ineffective | 70,142 | 27.6% | 2,652 | 9,752 |
| Rheumatoid arthritis | 29,254 | 11.5% | 2,111 | 6,669 |
| Off label use | 24,020 | 9.5% | 3,417 | 7,881 |
| Pain | 23,773 | 9.4% | 1,981 | 5,911 |
| Drug intolerance | 22,555 | 8.9% | 1,490 | 4,290 |
| Arthralgia | 21,831 | 8.6% | 1,776 | 5,744 |
| Fatigue | 19,885 | 7.8% | 2,005 | 5,458 |
| Nausea | 18,715 | 7.4% | 1,537 | 5,866 |
| Joint swelling | 17,657 | 7.0% | 1,963 | 4,442 |
| Drug hypersensitivity | 16,677 | 6.6% | 1,413 | 3,985 |
| Rash | 15,519 | 6.1% | 2,143 | 4,878 |
| Condition aggravated | 14,938 | 5.9% | 1,927 | 4,851 |
| Treatment failure | 14,672 | 5.8% | 1,172 | 2,598 |
| Alopecia | 14,360 | 5.7% | 1,673 | 3,214 |
| Abdominal discomfort | 13,237 | 5.2% | 1,784 | 3,600 |
Other Indications for METHOTREXATE
Rheumatoid arthritis (84,654)
Product used for unknown indication (56,611)
Acute lymphocytic leukaemia (11,187)
Psoriatic arthropathy (6,997)
Psoriasis (6,628)
Diffuse large b-cell lymphoma (2,761)
Crohn's disease (2,432)
Juvenile idiopathic arthritis (2,220)
Central nervous system lymphoma (2,075)
Systemic lupus erythematosus (1,440)
Other Drugs Used for Prophylaxis against graft versus host disease
CYCLOSPORINE (7,678)
MYCOPHENOLATE MOFETIL (6,298)
TACROLIMUS (5,234)
CYCLOPHOSPHAMIDE (2,727)
LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN (808)
METHYLPREDNISOLONE (753)
SIROLIMUS (710)
THYMOCYTE IMMUNE GLOBULIN NOS (614)
PREDNISONE (512)
MYCOPHENOLIC ACID (509)