Does METHOTREXATE Cause Extremity necrosis? 20 Reports in FDA Database
Grow Your Own Natural Pharmacy at Home
Medicinal Garden Kit — 10 healing herbs, 4,818 seeds + step-by-step guide.
According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Extremity necrosis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
20
Reports of Extremity necrosis with METHOTREXATE
0.0%
of all METHOTREXATE reports
2
Deaths
11
Hospitalizations
How Dangerous Is Extremity necrosis From METHOTREXATE?
Of the 20 reports, 2 (10.0%) resulted in death, 11 (55.0%) required hospitalization, and 2 (10.0%) were considered life-threatening.
Is Extremity necrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Extremity necrosis?
CANAGLIFLOZIN (95)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (84)
CARBOPLATIN (46)
PEMETREXED (45)
ADALIMUMAB (42)
GEMCITABINE (40)
METHYLPREDNISOLONE (40)
EPINEPHRINE (39)
PEMBROLIZUMAB (37)
NOREPINEPHRINE (34)
Which METHOTREXATE Alternatives Have Lower Extremity necrosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA