Does METHOTREXATE Cause Hypervolaemia? 77 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 77 reports of Hypervolaemia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
77
Reports of Hypervolaemia with METHOTREXATE
0.0%
of all METHOTREXATE reports
9
Deaths
61
Hospitalizations
How Dangerous Is Hypervolaemia From METHOTREXATE?
Of the 77 reports, 9 (11.7%) resulted in death, 61 (79.2%) required hospitalization, and 8 (10.4%) were considered life-threatening.
Is Hypervolaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 77 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hypervolaemia?
TREPROSTINIL (580)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (428)
AMBRISENTAN (205)
MACITENTAN (202)
FUROSEMIDE (139)
AMLODIPINE (122)
CYCLOPHOSPHAMIDE (118)
SACUBITRIL\VALSARTAN (115)
TACROLIMUS (100)
PREDNISONE (98)
Which METHOTREXATE Alternatives Have Lower Hypervolaemia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA