Does METHYLNALTREXONE Cause Intestinal perforation? 6 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6 reports of Intestinal perforation have been filed in association with METHYLNALTREXONE (Relistor). This represents 0.7% of all adverse event reports for METHYLNALTREXONE.
6
Reports of Intestinal perforation with METHYLNALTREXONE
0.7%
of all METHYLNALTREXONE reports
3
Deaths
1
Hospitalizations
How Dangerous Is Intestinal perforation From METHYLNALTREXONE?
Of the 6 reports, 3 (50.0%) resulted in death, 1 (16.7%) required hospitalization.
Is Intestinal perforation Listed in the Official Label?
Yes, Intestinal perforation is listed as a known adverse reaction in the official FDA drug label for METHYLNALTREXONE.
What Other Side Effects Does METHYLNALTREXONE Cause?
Death (214)
Drug ineffective (148)
Constipation (57)
Abdominal pain (54)
Diarrhoea (41)
Nausea (35)
Abdominal pain upper (33)
Off label use (29)
Vomiting (29)
Pain (26)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which METHYLNALTREXONE Alternatives Have Lower Intestinal perforation Risk?
METHYLNALTREXONE vs METHYLPHENIDATE
METHYLNALTREXONE vs METHYLPREDNISOLONE
METHYLNALTREXONE vs METHYLPREDNISOLONE ACEPONATE
METHYLNALTREXONE vs METHYLPREDNISOLONE HEMISUCCINATE
METHYLNALTREXONE vs METILDIGOXIN