Does METHYLPREDNISOLONE Cause Hyperammonaemia? 109 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 109 reports of Hyperammonaemia have been filed in association with METHYLPREDNISOLONE (Medroloan II SUIK). This represents 0.2% of all adverse event reports for METHYLPREDNISOLONE.
109
Reports of Hyperammonaemia with METHYLPREDNISOLONE
0.2%
of all METHYLPREDNISOLONE reports
52
Deaths
73
Hospitalizations
How Dangerous Is Hyperammonaemia From METHYLPREDNISOLONE?
Of the 109 reports, 52 (47.7%) resulted in death, 73 (67.0%) required hospitalization, and 41 (37.6%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHYLPREDNISOLONE. However, 109 reports have been filed with the FAERS database.
What Other Side Effects Does METHYLPREDNISOLONE Cause?
Off label use (10,364)
Drug ineffective (9,959)
Product use in unapproved indication (4,115)
Condition aggravated (3,784)
Headache (3,419)
Fatigue (3,250)
Pyrexia (3,226)
Pain (3,165)
Nausea (3,105)
Pneumonia (3,006)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which METHYLPREDNISOLONE Alternatives Have Lower Hyperammonaemia Risk?
METHYLPREDNISOLONE vs METHYLPREDNISOLONE ACEPONATE
METHYLPREDNISOLONE vs METHYLPREDNISOLONE HEMISUCCINATE
METHYLPREDNISOLONE vs METILDIGOXIN
METHYLPREDNISOLONE vs METOCLOPRAMIDE
METHYLPREDNISOLONE vs METOLAZONE