Does MITOXANTRONE Cause Intestinal perforation? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Intestinal perforation have been filed in association with MITOXANTRONE (mitoXANTRONE). This represents 0.4% of all adverse event reports for MITOXANTRONE.
15
Reports of Intestinal perforation with MITOXANTRONE
0.4%
of all MITOXANTRONE reports
12
Deaths
13
Hospitalizations
How Dangerous Is Intestinal perforation From MITOXANTRONE?
Of the 15 reports, 12 (80.0%) resulted in death, 13 (86.7%) required hospitalization.
Is Intestinal perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MITOXANTRONE. However, 15 reports have been filed with the FAERS database.
What Other Side Effects Does MITOXANTRONE Cause?
Febrile neutropenia (668)
Off label use (368)
Neutropenia (296)
Drug ineffective (293)
Thrombocytopenia (256)
Sepsis (240)
Pyrexia (214)
Product use in unapproved indication (177)
Disease progression (173)
Acute myeloid leukaemia (167)
What Other Drugs Cause Intestinal perforation?
ADALIMUMAB (1,010)
BEVACIZUMAB (600)
RITUXIMAB (321)
TOCILIZUMAB (276)
PREDNISONE (266)
CYCLOPHOSPHAMIDE (262)
DOXORUBICIN (240)
LENVATINIB (228)
INFLIXIMAB (226)
PEMBROLIZUMAB (220)
Which MITOXANTRONE Alternatives Have Lower Intestinal perforation Risk?
MITOXANTRONE vs MITRAGYNINE\HERBALS
MITOXANTRONE vs MIZORIBINE
MITOXANTRONE vs MOBOCERTINIB
MITOXANTRONE vs MOCLOBEMIDE
MITOXANTRONE vs MODAFINIL