Does NIVOLUMAB Cause Hyperammonaemia? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Hyperammonaemia have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.0% of all adverse event reports for NIVOLUMAB.
22
Reports of Hyperammonaemia with NIVOLUMAB
0.0%
of all NIVOLUMAB reports
4
Deaths
16
Hospitalizations
How Dangerous Is Hyperammonaemia From NIVOLUMAB?
Of the 22 reports, 4 (18.2%) resulted in death, 16 (72.7%) required hospitalization, and 12 (54.5%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which NIVOLUMAB Alternatives Have Lower Hyperammonaemia Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE