Does NIVOLUMAB Cause Leukoencephalopathy? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Leukoencephalopathy have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.0% of all adverse event reports for NIVOLUMAB.
26
Reports of Leukoencephalopathy with NIVOLUMAB
0.0%
of all NIVOLUMAB reports
6
Deaths
10
Hospitalizations
How Dangerous Is Leukoencephalopathy From NIVOLUMAB?
Of the 26 reports, 6 (23.1%) resulted in death, 10 (38.5%) required hospitalization, and 2 (7.7%) were considered life-threatening.
Is Leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does NIVOLUMAB Cause?
Death (11,216)
Malignant neoplasm progression (9,363)
Off label use (5,208)
Diarrhoea (4,692)
Fatigue (3,709)
Pyrexia (3,454)
Intentional product use issue (3,297)
Rash (2,816)
Nausea (2,805)
Decreased appetite (2,619)
What Other Drugs Cause Leukoencephalopathy?
METHOTREXATE (717)
CYTARABINE (208)
VINCRISTINE (138)
CYCLOPHOSPHAMIDE (137)
RITUXIMAB (118)
DEXAMETHASONE (107)
FLUOROURACIL (103)
FLUDARABINE (89)
TACROLIMUS (79)
CAPECITABINE (77)
Which NIVOLUMAB Alternatives Have Lower Leukoencephalopathy Risk?
NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW
NIVOLUMAB vs NIZATIDINE
NIVOLUMAB vs NOMEGESTROL
NIVOLUMAB vs NORDAZEPAM
NIVOLUMAB vs NOREPINEPHRINE