Does OLANZAPINE Cause Hyperammonaemia? 107 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 107 reports of Hyperammonaemia have been filed in association with OLANZAPINE (Olanzapine). This represents 0.2% of all adverse event reports for OLANZAPINE.
107
Reports of Hyperammonaemia with OLANZAPINE
0.2%
of all OLANZAPINE reports
5
Deaths
73
Hospitalizations
How Dangerous Is Hyperammonaemia From OLANZAPINE?
Of the 107 reports, 5 (4.7%) resulted in death, 73 (68.2%) required hospitalization, and 24 (22.4%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for OLANZAPINE. However, 107 reports have been filed with the FAERS database.
What Other Side Effects Does OLANZAPINE Cause?
Drug ineffective (5,139)
Weight increased (3,588)
Off label use (3,256)
Toxicity to various agents (3,175)
Somnolence (2,612)
Sedation (2,130)
Suicide attempt (2,116)
Confusional state (1,898)
Condition aggravated (1,810)
Overdose (1,765)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
Which OLANZAPINE Alternatives Have Lower Hyperammonaemia Risk?
OLANZAPINE vs OLANZAPINE\SAMIDORPHAN L-MALATE
OLANZAPINE vs OLAPARIB
OLANZAPINE vs OLARATUMAB
OLANZAPINE vs OLECLUMAB
OLANZAPINE vs OLIVE OIL\SOYBEAN OIL